Get Athlon Sports’ expert NFL picks, predictions and betting advice for every Week 17 game, including a big Bears-49ers matchup.

The Minnesota Vikings ride into Week 17 with an injury report that is growing by the day, but at least they carry with them a three-game winning streak. The injuries are going to really be felt on Christmas Day when they deal with a Detroit Lions team that is playing with a chip on their shoulder.

The Bears have seen midseason breakouts from their top two draft picks — tight end Colston Loveland, limited to 116 yards and no touchdowns in the first six games, now has 382 yards and four scores in the last eight games. Wide receiver Luther Burden III has 328 receiving yards in the last six, although he'll miss Saturday's game.

Senior writer Larry Mayer previews the Bears' Week 16 showdown for first place in the NFC North against the Packers at Soldier Field.

The New Orleans Saints visit the Tennessee Titans at Nissan Stadium for Week 17 of the 2025 NFL season on Sunday, Dec. 28 at 12 p.m. CT.

Week 13 brings a slate of five Sunday games on FOX Sports, following a 31-24 Packers win over the Lions on Thanksgiving. The lone game in the late window might be the best of the day, with Seattle and Sam Darnold going up against the team he led to the playoffs last season in the Vikings.

On top of that, as the season has gone on, most rankings have placed the Seahawks and Rams as the two best teams in the NFL, in some order. It’s arguable that this is the best game of the entire NFL regular season, unless that title went to the first meeting between the teams.

New Orleans Saints head coach Kellen Moore's exclusive interview with team reporter Erin Summers ahead of the Saints' game against the New York Jets in Week 16 of the 2025 NFL season.