The human genome is no longer just a sequence to be read. It’s a dynamic structure that twists, folds, and reshapes itself in ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations ...

Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome at a specific time or under particular conditions. It involves the analysis of ...

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma. Unlike single-gene ...

Research has uncovered a previously unknown, widespread role of ORC in regulating human cell gene expression. New work has revealed a much wider role for origin-recognition complex (ORC) in regulating ...

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. This is the first detailed study ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.